看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。
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Currently available feasibility data for possible combination strategies.
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Combination Feasibility according to preliminary data
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Bevacizumab + sorafenib Yes, reduced dose , H/ X' }/ l: b; t. b
Bevacizumab + sunitinib† No - @ ]) @7 V; x2 [. G
Bevacizumab + temsirolimus Yes
0 j* u8 w1 R( ?% jBevacizumab + everolimus Yes
9 x E f+ F( e1 [, OSorafenib + sunitinib ? & E) I: k$ G" ^* V8 j2 B, f
Sorafenib + temsirolimus Yes, reduced dose 6 V0 d* ^) I. l5 o8 Z- g
Sorafenib + everolimus Yes, reduced dose ) u2 E7 [) a2 o6 n6 |4 I+ s$ d
Sunitinib + temsirolimus† No . |' }( G$ l9 ]. S( k
Sunitinib + everolimus ? ' e5 z' G/ Y5 q( E, [
Temsirolimus + everolimus ?
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5 a h$ ^0 _8 R y: v" M* j7 G z% Z†Led to US FDA warning.1 s) Z* ^1 w/ A+ @
?: As yet unattempted combination.' n4 S) J' [/ I8 O' i) R
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